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Stem Cells for Coronavirus in Mexico

Preliminary Mesenchymal stem cells treatment reports on Covid-19 patients has shown promising results. Medical Tourism Corporation is helping facilitate this treatment in Mexico in COFEPRIS (Mexican FDA) approved facility.

With the positive results in stem cell treatment o7 patients with COVID-19 in the following

Study on Stem Cells Treating 7 Patients with COVID-19 Pneumonia
Patient Condition
  • One Critically ill patient
  • Four  Severely affected
  • Two mildly affected
  • Three in placebo-controlled group (severely affected)
Treatment
  1. Mesenchymal stem cell transplantation.
  2. Inflammation assessed within 14 days after transplantation
  3. A placebo-controlled group maintained with similar settings
Result
  1. Virtually all symptoms subsided by 2-4 days after receiving MSC infusion[1]Journal of Aging and Disease
    Mesenchymal Stem Cell Infusion Shows Promise for Combating Coronavirus (COVID-19)- Induced Pneumonia
    “Notably, the study found that virtually all symptoms subsided by 2-4 days after receiving MSC infusion with no apparent adverse effects…”
    View in Article
  2. No apparent adverse effects.
  3. Chest pneumonia infiltration subsided.
  4. Extraordinary  improvement in an elderly patient with critical condition post-infection

Other studies that strengthen the stem cell approach for COVID-19:

Patient Pre-treatment Treatment Post-treatment
1. Case Study on a female patient Acute COVID19 syndrome 21 days of treatment with umbilical cord MSCs 1. Laboratory tests and CT images provided extremely effective results[2]Stem Cell Reviews and Reports
Mesenchymal Stem Cell Therapy for COVID-19: Present or Future
“a case study was reported in China on a female patient with an acute COVID19 syndrome that the results of laboratory tests and CT images provided extremely effective results after 21 days of treatment…”
View in Article
2. Case report on a 65-year-old female COVID-19 induced acute pneumonia with abnormal neutrophils and diminished lymphocytes Cord MSCs + α1 thymosin 5 × 107 cells, each three times
  1. Improved Vitals
  2. Neutrophils decreased to normal levels
  3. Lymphocytes increased to normal levels.
  4. Pneumonia relieved
  5. Discharged from ICU 2 days after the third injection[3]National Science Library,Chinese Academy of Sciences
    Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells
    “The significant clinical outcome and well tolerance were observed by the adoptive transfer of allogenic hUCMSCs. Conclusions Our results suggested that the adoptive transfer therapy of hUCMSCs might be an ideal choice to be used or combined with other immune-modulating agents to treat the critically ill COVID-19 patients….”
    View in Article

Some ongoing and planned studies for Mesenchymal stem cells on COVID-19:

Phase Patient Characteristics Treatment Country
Ongoing Pneumonia Patients Infected With COVID-19 I.V. transfusion one round (3 times) of 3.0*10E7 cells of MSCs[4]ClinicalTrials.gov
Mesenchymal Stem Cell Treatment for Pneumonia Patients Infected With COVID-19
“Objective: To note improvement of Clinical symptoms and Side effects in the MSCs treatment group…”
View in Article
Beijing, China
Planned COVID-19 patients with lung inflammation Umbilical cord-derived mesenchymal stem cells (UC-MSCs) Miami, USA
Planned Coronavirus Induced Severe Pneumonia Dental Pulp Mesenchymal Stem Cells[5]ClinicalTrials.gov
Novel Coronavirus Induced Severe Pneumonia Treated by Dental Pulp Mesenchymal Stem Cells
“Objective: To note the disappear time of ground-glass shadow in the lungs…”
View in Article
Shanghai, China

MTC-Partner -Dr Anand Shrivastava, chairman and co-founder of Global Institute Of Stem cell Therapy And Research (GIOSTAR), explains how mesenchymal cells can treat Coronavirus affected patients.

Check out this video for more.

Stem Cells

Stem cells are a broader term for different kind of cells present in the body. These have the ability to divide and differentiate into specialized cells like brain cells, blood cells, heart muscle cells or bone cells.

Stem cells are now being widely tested as a part of regenerative medicine. These have already been approved for the treatment of cancers of the blood and bone marrow. Many more diseases are being treated using stem cell therapy in Mexico which still need approval in the USA.

Apart from this, latest researches confirm that stem cells can be a potential treatment for are COVID-19 positive patient and have an underlying condition.

What are Mesenchymal Stem Cells?

Mesenchymal cells are a kind of adult stem cells. These are capable of forming our skeletal tissues, such as cartilage, bone, and fat.

These cells can be found in the bone marrow, fat tissues, fallopian tube, peripheral blood cells, and in the umbilical cord cells and can be easily extracted from these sites.

How can Mesenchymal cells treat coronavirus infected patients?

The mesenchymal cells are known to boost human immunity.

With the 7-patient study, researchers are able to solidify the following inference:

  • Mesenchymal cells are safe for critically-ill COVID-19 patients[7]Journal of Aging and Disease
    Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
    “…the intravenous transplantation of MSCs was safe and effective for treatment in patients with COVID-19 pneumonia, especially for the patients in critically severe condition….”
    View in Article
  • Alleviation of pneumonia-like symptoms associated with the virus
  • Down-regulation (“blocking”) of proinflammatory (bad) cytokines within 3-6 days
  • A dramatic increase in the expression of anti-inflammatory (good) cytokines

Do allogeneic mesenchymal stem cells have any side effects?

No, mesenchymal cells do not pose any threat to the host’s body when transferred from a different donor. It owes to the immuno-suppressive properties of these cells [8]International Journal of Biomedical Sciences
The Immune Properties of Mesenchymal Stem Cells
“they also elicit immuno-suppressive effects that allow them to bypass allogeneic barriers …”
View in Article
which does not initiate an antibody response in the host’s body.

What is Novel Coronavirus- COVID-19?

Coronavirus structure-Mesenchymal stem cells for coronavirus
Coronavirus structure
Picture Courtesy: Journal of Medical Virology

COVID-19 is a new strain of the virus that belongs to the coronavirus family. The symptoms of COVID-19 infection are as follows:

  • Dry Cough
  • High Fever
  • Sore Throat
  • Headache
  • Shortness of Breath
  • Low oxygen saturation
  • COVID19 induced  pneumonia

How does COVID-19 Virus cause death in humans?

COVID-19, officially known as Sars-CoV-2 does not cause the death of any person. The death is, however, caused by the body’s own immune response against this virus. The following procedure will shed some light on the mechanism.

Site of infection

On infection, the virus quickly moves to the windpipe or trachea and stays there for some time.

The person may not develop any symptoms at this time. This is called an infection. But, once the virus starts multiplying, symptoms may appear.[9]BBC
Coronavirus: What it does to the body
“It first infects the cells…infect yet more cells….”
View in Article
.

The incubation period or the period between infection and appearance of the first symptom varies from one person to another, but generally, it is 5 days.

Body’s Immune Response

Once this virus enters the human body, the natural defence system of the body triggers an immune response.

This further releases certain chemicals called cytokines and chemokines in the body.

Mucous Accumulation

Due to these chemicals, lungs are inflamed and these experience an excessive fluid build-up[10]The Hindu
Coronavirus | How does the immune system respond to a coronavirus attack?
“In the nose and upper regions of the…prevent their ingress…”
View in Article
. This fluid also houses T-cells which are potent natural killers. These TNKs, however, attack the body’s own cells along with killing the pathogens.

Dry Cough

The significant symptom of Coronavirus infection-a dry cough is initiated. In this way, the lungs are trying to evacuate the mucous out of the body.

This cough is a potential carrier of the COVID-19 virus and proper social distancing and other precautions should be taken to stop the spread.

Oxygen Stress and Death

Meanwhile, the TNKs are attacking the healthy cells of the body. Slowly and gradually, the lungs become dis-functional and are unable to exchange oxygen with the blood, causing oxygen stress.

The continuous lack of oxygen causes the death of the infected patient.


Who is at higher mortal risk with Coronavirus and Why?

It is observed that the mortality rate of old people, as well as patients with severe underlying conditions like Type-2 diabetes or chronic lung disease, is high due to coronavirus-related symptoms. [11]Centres for Disease Control and Prevention
People Who Are at Higher Risk for Severe Illness
“Based on what we know now, those at high-risk…particularly if not well controlled …”
View in Article

Why Choose Mesenchymal cells for Coronavirus in Mexico?

There are many other reasons why Mexico is the best place for receiving mesenchymal stem cell treatment for COVID-19 infection.

Approved Technology

Using stem cell to treat different diseases is a legalised procedure in Mexico. Also, the Mexican government is very flexible in using novel scientific research like Mesenchymal cells in COVID-19 patients.

This is, however, not true for the USA as stem cell technology is not approved by the US-FDA.

Licensed and Authorized Physicians

Our partner clinic has scientists working on stem cell technology for more than 12 years. They are licensed physicians and are authorized to treat patients using human cells.

Our partner clinic has already applied for IND approval by the US-FDA for stem cells in Type-2-Diabetes patients.[12]Giostar
GIOSTAR In Process of US FDA Approval for Type 2 Diabetes Clinical Trial
“in the process of approval from the United States Food and Drug Administration (FDA) to conduct type 2 diabetes clinical trials focused on the development of stem cell-based treatment.”
View in Article

Easy Travel Options

Our partner clinic has branches in Los Algodones and Playa del Carman- Cancun Riviera. Both of these locations are near the US Border and one can easily cross the US-Mexico border.

Note: The border is open for travel related to essential services including medical reasons.

Why choose MTC for Treatment of COVID-19 infection?

MTC has been aiding medical and dental tourism to clients from all over the world. There are many reasons why you should choose us for your treatment with Stem Cells for Coronavirus in Mexico:

  • We are in the industry for more than 14 years now. Our clients speak the best about our services. Check our past patient testimonials.
  • We collaborate only with licensed and authorized physicians. Contact our case managers for more information on license and certifications of our partner doctors.
  • We provide the best bargain in the industry. We negotiate the best prices in the industry that suit your budget.
  • Tourism activities can be arranged
  • Free-shuttle service
  • Aid with accommodation

Contact us for more information on medical tourism.

Preventing the spread of Coronavirus

Corona Virus Infographic

Stem Cells for other diseases

Our partner clinic has been treating patients suffering from different diseases with stem cells in their Mexico based centres. Some of these diseases are mentioned below:

  1.  Amyotrophic Lateral Sclerosis (ALS)
  2. Arthritis
  3. Autism
  4. Cerebral Palsy
  5. Chronic Heart Failure
  6. Chronic Pain
  7. Chronic Obstructive Pulmonary Disease (COPD)
  8. Crohn’s Disease
  9. Type-2 Diabetes
  10. Liver Disease
  11. Leukemia
  12. Lupus
  13. Lymphoma
  14.  Neuropathy




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Coronavirus: Medical Tourism Corporation continues to offer its services. We are receiving enquiries & are arranging future bookings.

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