Stem Cells for Muscular Dystrophy in Mexico

Muscular Dystrophy is a collaborative term for progressive weakness and wasted muscle mass. Males are mostly affected and their first symptoms appear in their childhood.

Stem Cells for Muscular Dystrophy in Mexico helps in generating new muscle cells. These cells imitate the functions of the normal muscle cells and help in regaining the lost functionality as well.

Symptoms of Muscular Dystrophy

The signs and symptoms of MD include:

• Difficulty in getting up or lying
• Problems in running and jumping
• Muscle stiffness and pain
• Larger calf muscles
• Walking on toes

Types of Muscular Dystrophy

• Duchenne dystrophy: This is the most common type of MD which affects 1 in 3500 males. It is an inherited disease and the girls are usually the carrier of the genes for MD. The symptoms appear in early childhood and by the age of 11 or 12, the child completely loses the ability to walk and become wheel-chair ridden. With age, the teen develops dilated cardiomyopathy and breathing problems. Usually, the patient succumbs to these symptoms in the early 20s. Stem Cells for Muscular Dystrophy in Mexico can help patients with Duchenne dystrophy and increase the life expectancy of the child.
• Myotonic dystrophy: This type involves muscle wasting and progressive muscle weakness. The smaller muscles are primarily affected. The person experiences irregular heartbeat which needs to monitored regularly, difficulty in breathing and swallowing, muscle stiffness, etc.
• Becker dystrophy: It is similar to Duchenne dystrophy and is limited to males only. However, it is less severe in nature and progresses slowly and the survival lasts up till middle age.
• Oculopharyngeal: The eyelids and throat muscles are affected in this type of MD. This ultimately causes difficulty in swallowing and the person slowly dies due to lack of food. A study ^[1]Périé S, Trollet C, Mouly V, Vanneaux V, Mamchaoui K
  Autologous Myoblast Transplantation for Oculopharyngeal Muscular Dystrophy: a Phase I/IIa Clinical Study
  “This trial supports the hypothesis that a local injection of autologous myoblasts in the pharyngeal muscles is safe….”
  View in Article conducted on patients with Oculopharyngeal muscular dystrophy showed that autologous myoblast transplantation is a safe and efficient procedure. This study is also registered on Clinical Trials.gov
• Emery-Dreyfuss: Person has wasted shoulder, upper arm, and shin muscles and also suffer from joint deformities. Cardiac problems may become a cause of sudden death.
• Congenital: The life span is shortened but the disease progresses slowly. It includes wasting of muscles and joint deformities.

References:

• Mayo Clinic: Muscular dystrophy
• Molecular Therapy Journal: Autologous Myoblast Transplantation for Oculopharyngeal Muscular Dystrophy: a Phase I/IIa Clinical Study
• NHS UK: Muscular dystrophy
• University of Rochester Medical Center: Types of Muscular Dystrophy and Neuromuscular Diseases