New Gold Injections for Knee Pain in Mexico

Avoid Knee Replacement With a Cheaper, Long-term Option!

Stiffness of your knee or hip causing multiple problems? Painful joints can make it hard to walk or even sleep. It worsens when one has to deal with the high costs & fear of surgery. But why get a new knee when your old joint can live again? In 2021, patients find a non-surgical alternative to Knee/ Hip Replacement Surgery!

Success Story With Gold Injection – US Patient

This minimally invasive technique can reduce or eliminate your chances of a TKR. In this article, we focus on how it benefits patients with knee pain. Although you should know it helps arthritic patients with hip pain too.

What are Gold shots for Knee Pain in Mexico?

Gold shots in Mexico are the new alternative to knee replacement therapy. It is a minimally invasive technique that can postpone your complete knee replacement. To much surprise, it has the potential to offer you relief for ten years or more!

Gold salt is considered as a DMARD^[1]ACS Omega Journal Dose-Dependent Efficacy of Gold Clusters on Rheumatoid Arthritis Therapy “…It is worth noting that the Au cluster showed more efficacy in bone protection than the clinical anchor drug for RA therapy, methotrexate. ..” View in Article which means it has the property to modify the rheumatic disease. Although how new gold injections work is different and may we suggest, better!

Gold Particles Injection therapy is a one-time procedure. In this, you get a low dose of tiny particles of 99.99% pure elemental gold. The physician will implant this directly into your affected joint only.

According to Dr. Chris Fredrickson, the treatment is safe, and it can help relieve arthritic pain in the long term. It helps avoid an invasive knee or hip replacement and the high costs.

Should You Use Gold Injections for Knee Pain?

Yes, Gold Injections could be the solution to your painful knee! It is an outcome of years of research by Danish & American medical scientists. Pilot human clinical trials are very promising.

Advanced clinical trials are in the works of getting FDA approval. Currently, you can avail of it in Mexico & Denmark. Here an American medical scientist administers the injection.

Cause of Joint Pain – Rheumatoid Arthritis vs. Osteoarthritis

Rheumatoid arthritis and osteoarthritis are two common forms of arthritis. Although they can cause similar symptoms, there are some differences between the two.

Rheumatoid arthritis is an inflammatory disease in which your immune system attacks your joints, especially the hands, wrists, and feet. People with rheumatoid arthritis can have joint stiffness that lasts for hours.^[2]Havard Edu Explain the pain “Sometimes people with osteoarthritis also notice the same type of stiffness during the day after resting the joint for an hour or so. In rheumatoid arthritis, however, morning stiffness doesn’t begin to improve for an hour or longer.” View in Article

Osteoarthritis is a chronic disease that also causes joints to become painful and stiff. The joints that are most often affected are the knee and hips. Problems in the small joints of the hands are also common.^[3]NHS – UK Overview – Osteoarthritis “Almost any joint can be affected by osteoarthritis, but the condition most often causes problems in the knees, hips and small joints of the hands.” View in Article

Osteoarthritis can have a significant impact on your quality of life and productivity. Chronic pain makes it challenging to complete even the simplest daily activities. That is why osteoarthritis is the leading cause of disability worldwide.^[4]PubMed The epidemiology and impact of pain in osteoarthritis “Osteoarthritis (OA) is the most common form of arthritis and a leading cause of disability worldwide, largely due to pain, the primary symptom of the disease.” View in Article

As discussed previously, there is no cure for these diseases. Many patients rely on painkillers, which have limited efficacy. Thus, the use of injections is a promising alternative to reduce inflammation and pain in your joints.^[5]Research Gate Injectable gold for rheumatoid arthritis “Four trials and 415 patients were included. A statistically significant benefit was observed for injectable gold when compared to placebo… injectable gold has an important clinically and statistically significant benefit in the short term treatment of patients with rheumatoid arthritis” View in Article

“One of the greatest things about this treatment is that it allows people to have the freedom and mobility without the pain that they were experiencing before. We’ve had people be able to go up and down stairs, not just like one floor, but go up and downstairs at a lighthouse.”

– Dr. Robert MacLauchlan says.

Partner Hospital in Mexico for Gold Injections

Under the leadership of Dr. Sten Rasmussen in Denmark and Dr. Chris Frederickson in America, our partner hospital has developed effective gold microbead injections for osteoarthritis treatment.

Goldflex Lifesciences currently has a license to two issued patents and owns 4 pending patents in the United States.

The team of scientists and treating doctors are in this industry for more than 10 years now and have treated many patients in partnership with Aarhus University in Denmark.

Goldflex Team

Meet the Founder- Dr. Christopher Fredrickson

Dr. Fredrickson is a graduate of Harvard College and the University of Chicago (UChicago). He serves as the Chief Executive Officer at Gold Flex Life Sciences, Inc in the USA. Dr. discovered the zinc-secreting nerve cells of the brain in 1983. For this, he is acknowledged as the leading authority on zinc in the world.

Moreover, for his contributions to zinc biology, Dr. Fredrickson has an award named after him. It is called the “The Fredrickson Prize”^[7]International Journal of Molecular Sciences Report for the Sixth Meeting of the International Society for Zinc Biology (ISZB-2019) “…The Frederickson Prize… The prize is named after Christopher F. Frederickson, one of the founders of the zinc signal conferences, which finally became ISZB…” View in Article.

Dr. Robert Maclaughlan

Dr. Robert McLauchlan is the chief operating officer at Goldflex Lifesciences. He is also a former nuclear engineer serving onboard submarines in the United States Navy. He was then retained with high tech and start-ups as an intellectual property attorney prior to attending medical school at the University of Texas at Galveston

Who is an Ideal Candidate for Gold Injections?

If you are thinking about whether you qualify for the treatment or now, then according to the doctors at Goldflex, you are an ideal candidate if you:

• Severe or chronic osteoarthritis
• You care on the verge of getting a knee replacement
• If you are a professional athlete or paratrooper
• If you have painful knees that have not responded to any other medical treatment

Patients with a high BMI should not consider this as a weight loss alternative. Gold injections for the knee improve the quality of life by decreasing the pain. This encourages a healthy life schedule which may help weight loss.

Plan Your Gold Injections Treatment in Mexico

The gold injection is a single sitting procedure. Your overall procedure will look like this:

Prerequisites

You will be required to submit the following documents before you fly to Mexico* for the Gold injection treatment for your Osteoarthritis:

• Gold Flex Life Sciences Registration Forms (electronically fill-able PDF)
• Copy of Passport
• Previous medical history
• Current X-Rays of affected joint(s)
• COVID-19 test results; within 72 hours of departure or proof of vaccination

After the doctor approves your X-rays and lab reports, you will be prepped for the gold injections.

*Please Note: If you are arriving on the procedure day, please ensure that you reach well before your appointment time to avoid delays.

Injection Day

The doctor will put 20 micrograms of proprietory gold beads in your joints via an intra-articular route. These gold beads act as a drug delivery system for the gold ion complex released when the joint is inflamed.

Return Flight

You can head back home on the same day you receive your injections. This is an outpatient treatment.

After-effects

According to the Goldflex team, patients can see the difference in the first hour of their injection. Still, you should wait for at least 3-5 days before you can see a major difference in your gait.

Precautions

Gold is an inert metal, and it does not have any side effects. However, our doctors recommend that you refrain from heavy exercise or very long walks after the injections.

This is because you may not be using your leg muscles due to the chronic inflammation you had, which may have weakened your muscles.

So once the pain had subsided due to the gold microbeads, you may be tempted to move around, but over-usage of weakened muscles may cause muscle cramps.

What Are the Benefits of Gold Therapy?

A pilot study conducted at the Aalborg University Hospital, Aalborg, Denmark investigated the role of gold ions in treating knee osteoarthritis. Thirty patients with moderate to severe knee osteoarthritis received a single injection of metallic gold (20 mg) into the knee joint. The researchers observed^[8]Aalborg University Results “Pain and function improved in 25 of 30 patients. Womac pain decreased from 9 (6-16) to 3 (0-15), stiffness from 4 (1-8) to 2 (0-8), function from 29 (14-51) to 11 (0- 41) (Figure 4), PainDetect decreased from 10 (1-26) to 3 (0-19) (Figure 5). “ View in Article the following benefits of the therapy:

An improvement in the WOMAC score – a self questionnaire that evaluates the condition of patients with knee and hip osteoarthritis

• Improved joint pain
• Improved joint function
• An improvement in joint stiffness

The authors of the study concluded that intra-articular metallic gold improved joint pain, stiffness, and function. The therapy relieved pain and enhanced function in more than >80% of the patients.

Comparing Gold Therapy with Replacement Surgery

Partial Knee Replacement; TKR: Total Knee Replacement; THA: Total Hip arthroplasty

Sources: PubMed^[9]PubMed The total costs of drug therapy “The least expensive medication was penicillamine, at $10.62/week, and the most expensive was injectable gold, at $30.89/week.” View in Article; NHS^[10]NHS How long will it be before I feel normal? “You should be able to stop using your crutches or walking frame and resume normal leisure activities 6 weeks after surgery. However, it may take up to 3 months for pain and swelling to settle down.” View in Article; Google Scholar Articles^[11]U.S. National Library of Medicine Inflammation Impact on Pain in Knee Osteoarthritis “Condition ICMJE Inflammation; Osteo Arthritis Knee” View in Article

*The new gold particle therapy came in 2017 for human use. The long-term results data is thus unavailable. As with any intra-articular injection, you may face minor discomfort for a few hours.

If you ask about complication rates, the Goldflex doctor says “To date, we have not seen any adverse effects in more than 100 people treated with Gold Flex treatment in Denmark.” This is a long way from a 50% complication rate^[12]NCBI Gold Treatment in Rheumatoid Arthritis “It is a well-recognized fact that the use of gold salts in the treatment of rheumatoid arthritis is not without its dangers. The incidence of toxic reactions is high according to many observers appearing in about half the cases.” View in Article with old Gold injections and 9.5% (Hip) to 14.4% (Knee)^[13]BMC Complications to 6 months following total hip or knee arthroplasty “In the 8444 procedures included for analysis, major complications were reported by 9.5 and 14.4% of THA and TKA patients, respectively” View in Article for joint replacement surgery.

Depending on your inflammation, the dose requirements may vary. In a study of 30 patients, 28 are pain-free to date. The treatment thus boasts a >80% success rate with a single shot.

Hyaluronic Acid Vs Gold Injection

Hyaluronic Injection (HA)

Hyaluronic acid is shown to be a promising treatment for arthritic joint pain. Several studies have been conducted to prove the efficacy of these intra-articular injections.^[14]Journal of Clinical and Translational Medicine Recent advances in hyaluronic acid-based therapy for osteoarthritis “…Many trials have been…injection of HA in alleviating the symptoms in hip osteoarthritis..” View in Article

However, the main drawback of hyaluronic injections is that it only provides symptomatic benefit without the systemic^[15]Journal of Drugs and Aging Safety of Intra-articular Hyaluronic Acid Injections in Osteoarthritis: Outcomes of a Systematic Review and Meta-Analysis “…Intra-articular hyaluronic acid (IAHA) injection presents…systemic AEs associated with IA corticosteroids..” View in Article. Moreover, the effect wears off after 3- 5 weeks. Therefore, to maintain the pain-free effect of HLA, multiple injections are needed.

The HA injections can have severe adverse events like septic arthritis, ^[16]Journal of Clinical Orthopaedics and Related Research Efficacy of intraarticular hyaluronic acid injections in knee osteoarthritis “…is not without complication because… adverse reactions…poor clinical response.” View in Article. Also, it is inadvisable for patients with the complete collapse of joint space or bone loss due to the poor clinical response.

Gold Injections

Gold injections belong to a special drug class known as disease-modifying anti-rheumatic drugs (DMARDs). This means rather than providing symptomatic relief,  the gold injections cure the underlying problem which is the reason behind the discomfort.

A pilot study conducted at the University of Alborg, Denmark showed that the intra-articular injections in patients with osteoarthritis showed decreased inflammation and improved pain threshold.^[17]Aalborg University Hospital Intra-articular metallic gold micro particles relieve pain and enhance function in patients with knee osteoarthritis: A pilot study “… Intraarticular gold particles may modify …OA patients…” View in Article

You require only a single, low-dose gold injection whose effects will be visible in 2-3 days of the treatment. Unlike other DMARDS or HA injections, you do not need multiple drug applications.

References:

ACS Omega Journal: Dose-Dependent Efficacy of Gold Clusters on Rheumatoid Arthritis Therapy

Havard Edu: Explain the pain-Is it osteoarthritis or rheumatoid arthritis?

NHS UK: Overview – Osteoarthritis

PubMed: The epidemiology and impact of pain in osteoarthritis

Research Gate: Injectable gold for rheumatoid arthritis

Medical News Today: Can gold injections treat rheumatoid arthritis?

NCBI: Report for the Sixth Meeting of the International Society for Zinc Biology

PubMed: The total costs of drug therapy

NHS: How long will it be before I feel normal?

U.S. National Library of Medicine: Inflammation Impact on Pain in Knee Osteoarthritis

NCBI: Gold Treatment in Rheumatoid Arthritis

BMC: Complications to 6 months following total hip or knee arthroplasty

NCBI: Recent advances in hyaluronic acid-based therapy for osteoarthritis

Journal of Drugs and Aging: Safety of Intra-articular Hyaluronic Acid Injections in Osteoarthritis

PubMed: Efficacy of intraarticular hyaluronic acid injections in knee osteoarthritis

Aalborg University Hospital: A Pilot Study